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Comparative Study in Different Filters for Efficient Sterile Filtration

초록/요약

Simple membrane filtration is suitable as a terminal sterilization method for radiopharmaceuticals due to their short half-life and radiation exposure of process operator. However, it often adheres to the filter membrane and causes a considerable loss of radioactivity. We herein describe the investigation of sterile filtration performance varying individual sterile filters in order to identify the optimal sterile filter on demand for lipophilic radiopharmaceuticals. © 2020 Korean Chemical Society, Seoul & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

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