Associations of 25-Hydroxyvitamin D Levels and Arthritis with Sleep Duration: The Korean National Health and Nutrition Examination Survey 2008-2014
- 주제(키워드) vitamin D , arthritis , sleep duration , Korean National Health and Nutrition Examination Survey , KNHANES
- 주제(기타) Clinical Neurology
- 주제(기타) Neurosciences
- 설명문(일반) [Kim, Sun-Young; Lim, Weon-Jeong] Ewha Womans Univ, Seoul Hosp, Coll Med, Dept Psychiat, Seoul, South Korea; [Lee, Mi Hyun; Lee, Yu Jin] Seoul Univ, Seoul Natl Univ Hosp, Coll Med, Dept Psychiat, 103 Daehak Ro, Seoul 03080, South Korea; [Lee, Mi Hyun; Lee, Yu Jin] Seoul Univ, Seoul Natl Univ Hosp, Coll Med, Ctr Sleep & Chronobiol, 103 Daehak Ro, Seoul 03080, South Korea; [Kim, Soo In] Ewha Womans Univ, Mokdong Hosp, Coll Med, Dept Psychiat, Seoul, South Korea
- 등재 SCIE, SCOPUS
- OA유형 gold, Green Published
- 발행기관 DOVE MEDICAL PRESS LTD
- 발행년도 2020
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000174663
- 본문언어 영어
- Published As http://dx.doi.org/10.2147/NSS.S275464
- PubMed https://pubmed.ncbi.nlm.nih.gov/33177906
초록/요약
Purpose: The mean sleep duration of Koreans is 7 hours 49 minutes, which is the lowest among Organization for Economic Cooperation and Development countries. Although vitamin D deficiency and arthritis are considered modifiable factors influencing restorative sleep, mean vitamin D levels are low (17.33 ng/mL) and arthritis is prevalent among Koreans. This study investigated whether vitamin D deficiency and arthritis increase the risk of short sleep duration. Patients and Methods: The current study used data from the Korean National Health and Nutrition Examination Survey (KNHANES) for 46,405 Korean adults. Vitamin D levels were measured using a radioimmunoassay kit. Sleep duration and arthritis history were assessed using a self-reported questionnaire. Sleep duration was categorized as optimal (7 to <9 hours/day), short (<7 hours/day), and long (>= 9 hours/day). Vitamin D levels were grouped as vitamin D sufficiency (>= 20 ng/mL), insufficiency (10-19.99 ng/mL), and deficiency (<10 ng/mL). Multiple imputation was used to compensate for missing data. Multinomial logistic regression was used to examine the associations of vitamin D and arthritis status with sleep duration. The regressions were adjusted for covariates, and each model was adjusted for vitamin D and arthritis. Results: Among these participants, 23,078 (49.73%) and 3518 (7.58%) had short and long sleep duration, respectively; 26,724 (57.59%) and 4349 (9.37%) exhibited vitamin D insufficiency and deficiency, respectively; and 4709 (10.15%) were arthritis patients. Compared with vitamin D sufficiency, vitamin D insufficiency and deficiency were associated with short sleep duration (vitamin D insufficiency group: OR = 1.07, 95% CI = 1.01-1.13; vitamin D deficiency group: OR = 1.13, 95% CI = 1.03-1.24). The presence of arthritis was associated with short sleep duration (OR = 1.14, 95% CI = 1.06-1.22) compared with its absence. The interaction between vitamin D deficiency and the presence of arthritis was significantly associated with short sleep duration. However, long sleep duration was not significantly associated with vitamin D levels or arthritis status. Conclusion: Low vitamin D levels and the presence of arthritis were associated with an increased risk of short sleep duration. Additionally, there was a positive interaction effect between vitamin D deficiency and arthritis on short sleep duration.
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