Design and synthesis of efficient heavy-atom-free photosensitizers for photodynamic therapy of cancer
- 등재 SCIE, SCOPUS
- 발행기관 Royal Society of Chemistry
- 발행년도 2020
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000174741
- 본문언어 영어
- Published As http://dx.doi.org/10.1039/d0cc04644b
- PubMed https://pubmed.ncbi.nlm.nih.gov/32857074
초록/요약
Novel thiocarbonyl derivatives (NIS and CRNS) with excellent ROS generation abilities are synthesized and studied as potential photosensitizers for one- and two-photon excited photodynamic therapy. In particular,NIS-MeandCRNSdisplay outstanding phototoxicity toward HeLa cells under two-photon excitation (800 nm) with negligible dark toxicity. © The Royal Society of Chemistry 2020.
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