Bioactive natural products from the genus Salinospora: a review
- 주제(키워드) Actinomycetes , Marine natural products , Salinispora , Salinispora arenicola , Salinispora pacifica , Salinispora tropica
- 등재 SCIE, SCOPUS, KCI등재
- 발행기관 Pharmaceutical Society of Korea
- 발행년도 2020
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000174918
- 본문언어 영어
- Published As http://dx.doi.org/10.1007/s12272-020-01288-1
- PubMed https://pubmed.ncbi.nlm.nih.gov/33237436
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Actinomycetes are an important source for bioactive secondary metabolites. Among them, the genus Salinispora is one of the first salt obligatory marine species worldwide and is typically found in various types of substrates in tropical and subtropical marine environments including sediments and marine organisms. This genus produces a wide range of chemical scaffolds and bioactive compounds such as lomaiviticins, cyclomarins, rifamycins, salinaphthoquinones, and salinosporamides. This review arranged Salinispora derived secondary metabolites according to the three species that comprise the genus. Moreover, muta- and semi-synthesis analogs derived from salinosporamide were also described in this review. © 2020, The Pharmaceutical Society of Korea.
more