Highly Efficient Aggregation-Induced Red-Emissive Organic Thermally Activated Delayed Fluorescence Materials with Prolonged Fluorescence Lifetime for Time-Resolved Luminescence Bioimaging
- 주제(키워드) thermally activated delayed fluorescence (TADF) , aggregation-induced emission , red emission , fluorescence imaging , time-resolved luminescence imaging
- 주제(기타) Nanoscience & Nanotechnology
- 주제(기타) Materials Science, Multidisciplinary
- 설명문(일반) [Qi, Sujie; Nguyen, Van-Nghia; Kim, Youngmee; Kim, Gyoungmi; Kim, Sung-Jin; Yoon, Juyoung] Ewha Womans Univ, Dept Chem & Nanosci, Seoul 03760, South Korea; [Kim, Sangin; Park, Sungnam] Korea Univ, Dept Chem, Seoul 02841, South Korea; [Niu, Guangle] Shandong Univ, Ctr Bio & Micro Nano Funct Mat, State Key Lab Crystal Mat, Jinan 250100, Peoples R China; [Nguyen, Van-Nghia] Duy Tan Univ, Inst Res & Dev, Da Nang 550000, Vietnam
- 등재 SCIE, SCOPUS
- 발행기관 AMER CHEMICAL SOC
- 발행년도 2020
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000175435
- 본문언어 영어
- Published As http://dx.doi.org/10.1021/acsami.0c15936
- PubMed https://pubmed.ncbi.nlm.nih.gov/33156606
초록/요약
Organic thermally activated delayed fluorescence (TADF) materials are emerging as potential candidates for time-resolved fluorescence imaging in biological systems. However, the development of purely organic TADF materials with bright aggregated-state emissions in the red/near-infrared (NIR) region remains challenging. Here, we report three donor-acceptor-type TADF molecules as promising candidates for time-resolved fluorescence imaging, which are engineered by direct connection of electron-donating moieties (phenoxazine or phenothiazine) and an electron-acceptor 1,8-naphthalimide (NI). Theoretically and experimentally, we elucidate that three TADF materials possessed remarkably small Delta E-ST to promote the occurrence of reverse intersystem crossing (RISC). Moreover, they all exhibit aggregation-induced red emissions and long delayed fluorescence lifetimes without the influence of molecular oxygen. More importantly, these long-lived and biocompatible TADF materials, especially the phenoxazine-substituted NI fluorophores, show great potential for high-contrast fluorescence lifetime imaging in living cells. This study provides further a molecular design strategy for purely organic TADF materials and expands the versatile biological application of long-lived fluorescence research in time-resolved luminescence imaging.
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