Imaging of intracellular singlet oxygen with bright BODIPY dyes
- 주제(키워드) Bodipy , Fluorescent probe , Photodynamic therapy , Reactive oxygen species , Singlet oxygen probe
- 등재 SCIE, SCOPUS
- 발행기관 Elsevier Ltd
- 발행년도 2021
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000175673
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.dyepig.2021.109158
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Singlet oxygen is a cytotoxic reactive species which is involved in the photodynamic therapy of cancer. It is also known to be produced endogenously in most eukaryotic cells and implicated in many biochemical processes, including apoptotic response. We now report that Bodipy based fluorescent dyes with singlet oxygen reactive modules, signal the intracellular generation of singlet oxygen through photosensitization. We believe long wavelength probes of singlet oxygen, based on this approach will be highly valuable. © 2021 Elsevier Ltd
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