Medication-related osteonecrosis of the maxilla: Prognosis of oral surgery combined with endoscopic sinus surgery
- 주제(키워드) endoscopic sinus surgery , maxilla , medication-related osteonecrosis of the jaw , sinusitis
- 등재 SCIE, SCOPUS
- 발행기관 Blackwell Publishing Ltd
- 발행년도 2020
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000175817
- 본문언어 영어
- Published As http://dx.doi.org/10.1111/odi.13615
- PubMed https://pubmed.ncbi.nlm.nih.gov/32810362
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Objectives: To evaluate the effect of functional endoscopic sinus surgery (FESS) on the resolution of maxillary medication-related osteonecrosis of the jaw (MRONJ). Patients and Methods: This study included 62 patients diagnosed with MRONJ in the maxillary posterior area with or without maxillary sinusitis (MS). All patients underwent oral surgery. The concomitant MS was evaluated, and if indicated, FESS was performed on the same operation. Follow-up included clinical and radiological examinations at 4 months postoperation. Results: Of the 62 patients, 24 (38.7%) showed no evidence of MS and 38 (61.3%) showed MS. Advanced MRONJ (stage 3), which has bony destruction of the sinus floor and signs of MS according to its definition, was seen in 27 patients (43.5%). In stage 3 MRONJ, patients with combined treatment of oral surgery and FESS compared to those treated with oral surgery alone showed higher percentage of resolution (84.2%, 37.5%, respectively) at 4 months postoperatively, and the results were statistically significant. Conclusion: Simultaneous management of MRONJ and sinusitis with combined treatment of oral surgery and FESS for the treatment of maxillary MRONJ can be an effective method, especially for advanced cases, to address its associated lesions. © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved
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