Evidence-Based Guidelines for the Treatment of Helicobacter pylori Infection in Korea 2020
- 주제(키워드) Helicobacter pylori , Guidelines , Treatment , Meta-analysis , Microbial sensitivity tests
- 주제(기타) Gastroenterology & Hepatology
- 설명문(일반) [Jung, Hye-Kyung] Ewha Womans Univ, Dept Internal Med, Sch Med, Seoul, South Korea; [Kang, Seung Joo] Seoul Natl Univ Hosp, Dept Internal Med, Gangnam Ctr, Seoul, South Korea; [Lee, Yong Chan; Kim, Jie-Hyun] Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; [Yang, Hyo-Joon] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Internal Med, Div Gastroenterol,Sch Med, Seoul, South Korea; [Yang, Hyo-Joon] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Gastrointestinal Canc Ctr, Sch Med, Seoul, South Korea; [Park, Seon-Young] Chonnam Natl Univ, Dept Internal Med, Med Sch, Gwangju, South Korea; [Shin, Cheol Min] Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, South Korea; [Kim, Sung Eun] Kosin Univ, Dept Internal Med, Coll Med, Busan, South Korea; [Lim, Hyun Chul] Yonsei Univ, Yongin Severance Hosp, Dept Internal Med, Coll Med, Yongin, South Korea; [Kim, Jie-Hyun] Yonsei Univ, Inst Gastroenterol, Coll Med, Seoul, South Korea; [Nam, Su Youn] Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Ctr Gastr Canc, Sch Med,Chilgok Hosp, Daegu, South Korea; [Shin, Woon Geon] Hallym Univ, Dept Internal Med, Coll Med, Seoul, South Korea; [Park, Jae Myung] Catholic Univ Korea, Coll Med, Dept Internal Med, Div Gastroenterol & Hepatol,Seoul St Marys Hosp, Seoul, South Korea; [Choi, Il Ju] Natl Canc Ctr, Ctr Gastr Canc, Goyang, South Korea; [Kim, Jae Gyu] Chung Ang Univ, Dept Internal Med, Coll Med, Seoul, South Korea; [Choi, Miyoung] Natl Evidence Based Healthcare Collaborating Agcy, Div Healthcare Technol Assessment Res, Seoul, South Korea
- 등재 SCIE, SCOPUS, KCI등재
- 발행기관 EDITORIAL OFFICE GUT & LIVER
- 발행년도 2021
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000181442
- 본문언어 영어
- Published As http://dx.doi.org/10.5009/gnl20288
초록/요약
Helicobacter pylori infection is one of the most common infectious diseases worldwide. Although the prevalence of H. pylori is gradually decreasing, approximately half of the world's population still becomes infected with this disease. H. pylori is responsible for substantial gastrointestinal morbidity worldwide, with a high disease burden. It is the most common cause of gastric and duodenal ulcers and gastric cancer. Since the revision of the H. pylori clinical practice guidelines in 2013 in Korea, the eradication rate of H. pylori has gradually decreased with the use of a clarithromycin-based triple therapy for 7 days. According to a nationwide randomized controlled study conducted by the Korean College of Helicobacter and Upper Gastrointestinal Research released in 2018, the intention-to-treat eradication rate was only 63.9%, which was mostly due to increased antimicrobial resistance, especially from clarithromycin. The clinical practice guidelines for the treatment of H. pylori were updated according to evidence-based medicine from a meta-analysis conducted on a target group receiving the latest level of eradication therapy. The draft recommendations developed based on the meta-analysis were finalized after an expert consensus on three recommendations regarding the indication for treatment and eight recommendations for the treatment itself. These guidelines were designed to provide clinical evidence for the treatment (including primary care treatment) of H. pylori infection to patients, nurses, medical school students, policymakers, and clinicians. These may differ from current medical insurance standards and will be revised if more evidence emerges in the future.
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