Gold(I)-Catalyzed Intramolecular Dehydrative Amination of Sulfamate Esters Tethered to Allylic Alcohols: A Strategy for the Synthesis of Cyclic Sulfamidates
- 주제(키워드) Amination , Cyclic sulfamidate , Gold , Homogeneous catalysis , Silver
- 후원정보 Ryu, J.-S.; College of Pharmacy & Graduate School of Pharmaceutical Sciences, 52 Ewhayeodae-gil, Seodaemun-gu, South Korea; email: ryuj@ewha.ac.kr
- 등재 SCIE, SCOPUS
- 발행기관 John Wiley and Sons Inc
- 발행년도 2021
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000181761
- 본문언어 영어
- Published As http://dx.doi.org/10.1002/adsc.202001330
초록/요약
An efficient synthesis protocol for cyclic sulfamidates has been developed via catalytic intramolecular cyclizations of sulfamate esters tethered to allylic alcohols. The reactions proceed smoothly at room temperature in the presence of (IPr)AuCl (5 mol%) and AgBF4 (5 mol%). This protocol features good to excellent yields, high selectivity, broad substrate scope, and mild reaction conditions. This method is also applicable to the synthesis of a seven-membered sulfamidate. (Figure presented.). © 2021 Wiley-VCH GmbH
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