Evaluation of Mechanical and Thermal Properties of Hydroxyapatite-levan Composite Bone Graft
- 주제(키워드) bone graft , composite scaffold , hydroxyapatite , levan , sintering
- 관리정보기술 faculty
- 등재 SCIE, SCOPUS, KCI등재
- 발행기관 Korean Society for Biotechnology and Bioengineering
- 발행년도 2021
- URI http://www.dcollection.net/handler/ewha/000000181793
- 본문언어 영어
- Published As http://dx.doi.org/10.1007/s12257-020-0094-6
초록/요약
Biodegradable materials have been received great attention as bone graft substitutes for bone regeneration and tissue engineering. However, their low mechanical property remains a major challenge for the use in load-bearing applications. Here, we developed mechanically reinforced composite scaffold containing adhesive levan as a binder for sintered hydroxyapatite (sHAp) and then examined the mechanical and thermal properties of the composite scaffold. We found that sHAp-levan composite scaffold exhibited remarkably enhanced mechanical strength, which is similar to that of polymethyl methacrylate (PMMA) bone cement. This composite scaffold can be utilized as a promising bone graft for bone regeneration and tissue engineering. © 2021, The Korean Society for Biotechnology and Bioengineering and Springer.
more