Formal synthesis of (±)-sedamine through gold(I)-catalyzed intramolecular dehydrative amination of sulfamate esters tethered to allylic alcohols
- 주제(키워드) Cyclic sulfamidate , Dehydrative amination , Gold , Sedamine , Silver
- 등재 SCIE, SCOPUS
- 발행기관 Elsevier Ltd
- 발행년도 2021
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000181848
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.tetlet.2021.153024
초록/요약
A concise formal synthesis of (±)-sedamine has been accomplished. The synthesis is straightforward and demonstrates high efficiency. Key steps involve gold(I)-catalyzed cyclization of sulfamate esters tethered to allylic alcohols, sulfamate N-alkylation, and ring-closing metathesis. © 2021 Elsevier Ltd
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