Catalyst-controlled divergent transformations ofN-sulfonyl-1,2,3-triazoles into isoquinolin-3-ones and 2-aminoindanones
- 등재 SCIE, SCOPUS
- 발행기관 Royal Society of Chemistry
- 발행년도 2021
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000181920
- 본문언어 영어
- Published As http://dx.doi.org/10.1039/d1ob00708d
초록/요약
Novel catalyst-controlled divergent intramolecular reactions ofN-sulfonyl-1,2,3-triazoles with tethered-allylic alcohol have been developed. In the presence of the Pd(0) catalyst alone, 1-vinylated 1,4-dihydroisoquinolin-3-ones were formed, whereas 3-vinylated 2-aminoindanones were accessed under tandem, one-pot, Rh(ii)/Pd(0) dual catalytic conditions. Based on deuterium-labelling experiments and isolation of the intermediate, a plausible reaction mechanism has been proposed. © The Royal Society of Chemistry 2021.
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