CT findings of acute radiation-induced pneumonitis in breast cancer
- 주제(기타) Radiology, Nuclear Medicine & Medical Imaging
- 설명문(일반) [Jung, Wonguen; Kim, Kyubo] Ewha Womans Univ, Dept Radiat Oncol, Coll Med, Seoul, South Korea; [Shim, Sung Shine] Ewha Womans Univ, Dept Radiol, Coll Med, Seoul, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 BRITISH INST RADIOLOGY
- 발행년도 2021
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000182296
- 본문언어 영어
- Published As http://dx.doi.org/10.1259/bjr.20200997
초록/요약
Objectives: To evaluate the CT findings of acute radiation pneumonitis (RP) in breast cancer patients undergoing post-operative radiotherapy, and to analyze clini-codosimetric factors associated with acute RP. Methods: Between 2015 and 2017, 61 patients with breast cancer who underwent follow-up chest CT at 3 months after radiotherapy were analyzed. The degree of acute RP on CT was evaluated by the change of extent and scoring system (grade 0, no RP; Grade 1, ground-glass opacities (GGOs); Grade 2, GGOs and/or consolidations; Grade 3, clear focal consolidation; Grade 4, dense consolidation). The dosimetric parameters were calculated from the dose-volume histogram of RT. Results: The acute RP on CT was scored as follows: Grade 0, in 37.7%, Grade 1 in 13.1%, Grade 2 in 44.3%, and Grade 3 in 4.9%. The median extent of RP in patients with Grades 1 to 3 was 6.2 ml (range, 0.2-95.9). There were no clinicodosimetric factors significantly associated with the presence of RP or its severity. One patient developed symptomatic RP. Conclusion: This study showed no correlation between acute RP and clinicodosimetric factors, and acute RP based on CT findings were much more common than symptomatic RP. Advances in knowledge: CT findings of acute RP or extent of RP were not significantly related to clinicodosimetric factors in breast cancer patients.
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