Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial
- 주제(키워드) Breast Neoplasms , Sentinel Lymph Node Biopsy , Ultrasonography
- 주제(기타) Oncology
- 설명문(일반) [Chang, Jung Min; Moon, Woo Kyung] Seoul Natl Univ Hosp, Dept Radiol, 101 Daehak Ro, Seoul 03080, South Korea; [Shin, Hee Jung; Kim, Hak Hee] Asan Med Ctr, Dept Radiol, Seoul, South Korea; [Shin, Hee Jung; Kim, Hak Hee] Asan Med Ctr, Res Inst Radiol, Seoul, South Korea; [Choi, Ji Soo; Han, Boo-Kyung] Samsung Med Ctr, Dept Radiol, Seoul, South Korea; [Choi, Ji Soo; Han, Boo-Kyung] Samsung Med Ctr, Ctr Imaging Sci, Seoul, South Korea; [Shin, Sung Ui] Seoul Natl Univ, Dept Radiol, Bundang Hosp, Seoul, South Korea; [Choi, Bo Hwa] Natl Canc Ctr, Dept Radiol, Goyang, South Korea; [Kim, Min Jung; Yoon, Jung Hyun] Severance Hosp, Res Inst Radiol Sci, Dept Radiol, Seoul, South Korea; [Chung, Jin] Ewha Womans Univ, Mokdong Hosp, Dept Radiol, Sch Med, Seoul, South Korea; [Kim, Tae Hee] Ajou Univ, Dept Radiol, Med Ctr, Suwon, South Korea
- 등재 SCIE, SCOPUS, KCI등재
- OA유형 gold, Green Published
- 발행기관 KOREAN BREAST CANCER SOC
- 발행년도 2021
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000190797
- 본문언어 영어
- Published As https://doi.org/10.4048/jbc.2021.24.e47
- PubMed https://pubmed.ncbi.nlm.nih.gov/34877830
초록/요약
Axillary ultrasonography (US) is the most commonly used imaging modality for nodal evaluation in patients with breast cancer. No Axillary Surgical Treatment in Clinically Lymph Node-Negative Patients after Ultrasonography (NAUTILUS) is a prospective, multicenter, randomized controlled trial investigating whether sentinel lymph node biopsy (SLNB) can be safely omitted in patients with clinically and sonographically node-negative T1-2 breast cancer treated with breast-conserving therapy. In this trial, a standardized imaging protocol and criteria were established for the evaluation of axillary lymph nodes. Women lacking palpable lymph nodes underwent axillary US to dismiss suspicious nodal involvement. Patients with a round hypoechoic node with effaced hilum or indistinct margins were excluded. Patients with T1 tumors and a single node with a cortical thickness >= 3 mm underwent US-guided biopsy. Finally, patients with negative axillary US findings were included. The NAUTILUS axillary US nodal assessment criteria facilitate the proper selection of candidates who can omit SLNB.
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