Association between CHADS(2), CHA(2)DS(2)-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients
- 주제(키워드) ischemic stroke , stroke risk score , recanalization , thrombectomy
- 주제(기타) Medicine, General & Internal
- 설명문(일반) [Kim, Hyung Jun; Park, Moo-Seok; Song, Tae-Jin] Ewha Womans Univ, Coll Med, Seoul Hosp, Dept Neurol, Seoul 07804, South Korea; [Yoo, Joonsang] Yonsei Univ, Coll Med, Yongin Severance Hosp, Dept Neurol, Yongin 16995, South Korea; [Kim, Young Dae; Heo, JoonNyung; Kim, Jinkwon; Nam, Hyo Suk] Yonsei Univ, Dept Neurol, Coll Med, Seoul 03722, South Korea; [Park, Hyungjong; Sohn, Sung-Il; Hong, Jeong-Ho] Keimyung Univ, Dept Neurol, Sch Med, Daegu 42601, South Korea; [Kim, Byung Moon; Kim, Dong Joon] Yonsei Univ, Dept Radiol, Coll Med, Seoul 03722, South Korea; [Bang, Oh Young; Seo, Woo-Keun; Chung, Jong-Won] Sungkyunkwan Univ, Sch Med, Dept Neurol, Samsung Med Ctr, Seoul 06351, South Korea; [Kim, Hyeon Chang] Yonsei Univ, Coll Med, Dept Prevent Med, Seoul 03722, South Korea; [Han, Euna] Yonsei Univ, Yonsei Inst Pharmaceut Res, Coll Pharm, Incheon 21983, South Korea; [Choi, Jin Kyo] Seoul Med Ctr, Dept Neurol, Seoul 02053, South Korea; [Lee, Kyung-Yul; Jung, Yo Han] Yonsei Univ, Gangnam Severance Hosp, Dept Neurol, Coll Med, Seoul 06273, South Korea; [Lee, Hye Sun] Yonsei Univ, Dept Res Affairs, Biostat Collaborat Unit, Coll Med, Seoul 03722, South Korea; [Shin, Dong Hoon] Gachon Univ, Gil Med Ctr, Dept Neurol, Incheon 21565, South Korea; [Choi, Hye-Yeon] Kyung Hee Univ, Kyung Hee Univ Hosp Gangdong, Dept Neurol, Sch Med, Seoul 05278, South Korea; [Lee, Jong Yun] Natl Med Ctr, Dept Neurol, Seoul 04564, South Korea; [Baek, Jang-Hyun] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Neurol, Sch Med, Seoul 03181, South Korea; [Kim, Gyu Sik; Seo, Kwon-Duk] Ilsan Hosp, Natl Hlth Insurance Serv, Dept Neurol, Goyang 10444, South Korea; [Kim, Seo Hyun] Yonsei Univ, Dept Neurol, Wonju Coll Med, Wonju 26426, South Korea; [Han, Sang Won; Park, Joong Hyun] Inje Univ, Sanggye Paik Hosp, Dept Neurol, Coll Med, Seoul 01757, South Korea; [Cho, Han-Jin] Pusan Natl Univ, Sch Med, Dept Neurol, Busan 49241, South Korea; [Ahn, Seong Hwan] Chosun Univ, Dept Neurol, Sch Med, Gwangju 61453, South Korea; [Lee, Sung Ik] Wonkwang Univ, Sanbon Hosp, Dept Neurol, Sch Med, Gunpo 15865, South Korea; [Chang, Yoonkyung] Ewha Womans Univ, Mokdong Hosp, Dept Neurol, Coll Med, Seoul 07985, South Korea
- 등재 SCIE, SCOPUS
- OA유형 Green Published, gold
- 발행기관 MDPI
- 발행년도 2022
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000190798
- 본문언어 영어
- Published As https://doi.org/10.3390/jcm11010274
- PubMed https://pubmed.ncbi.nlm.nih.gov/35012015
초록/요약
Background: The CHADS(2), CHA(2)DS(2)-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT). Methods: From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutively included 501 patients who underwent EVT. We identified pre-admission stroke risk scores in each included patient. Results: Among 501 patients who underwent EVT, 410 (81.8%) patients achieved successful recanalization (mTICI >= 2b). Adjusting for body mass index and p < 0.1 in univariable analysis revealed the association between all stroke risk scores and unsuccessful recanalization (CHADS(2) score: odds ratio (OR) 1.551, 95% confidence interval (CI) 1.198-2.009, p = 0.001; CHA(2)DS(2)VASc score: OR 1.269, 95% CI 1.080-1.492, p = 0.004; ATRIA score: OR 1.089, 95% CI 1.011-1.174, p = 0.024; and Essen score: OR 1.469, 95% CI 1.167-1.849, p = 0.001). The CHADS(2) score had the highest AUC value and differed significantly only from the Essen score (AUC of CHADS(2) score; 0.618, 95% CI 0.554-0.681). Conclusion: All stroke risk scores were associated with unsuccessful recanalization after EVT. Our study suggests that these stroke risk scores could be used to predict recanalization in stroke patients undergoing EVT.
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