Breast Cancer after Radiation Therapy in a Patient with Li-Fraumeni Syndrome: A Case Report
- 주제(키워드) Breast Neoplasms , Li-Fraumeni Syndrome , Sarcoma , Second Primary
- 등재 SCOPUS, KCI등재
- 발행기관 Korean Radiological Society
- 발행년도 2022
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000190848
- 본문언어 영어
- Published As https://doi.org/10.3348/jksr.2021.0045
초록/요약
Li-Fraumeni syndrome (LFS) is an inherited autosomal-dominant tumor-predisposition disorder caused by germline mutations in the TP53 tumor suppressor gene. Since patients with LFS are likely to develop therapy-related cancers, radiation therapy should be avoided if breast cancer is found in these individuals. Herein, we present a case of secondary breast cancer in an LFS patient after radiation and chemotherapy for the first diagnosed breast sarcoma. © 2022 Korean Radiological Society. All right reserved.
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