Emerging strategies for biomaterial-assisted cancer immunotherapy
- 주제(키워드) Biomaterials , Cancer Immunotherapy , Combination Therapy , Immuno-engineering , Localized Delivery
- 관리정보기술 faculty
- 등재 SCIE, SCOPUS, KCI등재
- 발행기관 Springer
- 발행년도 2022
- URI http://www.dcollection.net/handler/ewha/000000191101
- 본문언어 영어
- Published As https://doi.org/10.1007/s11814-021-0985-z
초록/요약
Among many treatment options to prevent cancer progression, cancer immunotherapy has become a powerful clinical strategy due to its favorable clinical outcomes. The number of clinical trials in immune checkpoint blockade (ICB) therapy and chimeric antigen receptor (CAR)-T cell therapy has been remarkably increasing in recent years. However, the currently available options for these treatments pose significant challenges related to immune-related adverse effects and limited therapeutic efficacy. Excellent delivery technologies by leveraging biomaterials to mitigate these limitations could potentially advance current cancer immunotherapies for a wide range of applications. In this review, we analyze various strategies of biomaterial-assisted cancer immunotherapy for localized, targeted, and combined treatments and then summarize the promises and challenges for integrating biomaterial-based delivery technologies into cancer immunotherapy. © 2022, The Korean Institute of Chemical Engineers.
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