Microbial cell factories for the production of three-carbon backbone organic acids from agro-industrial wastes
- 주제(키워드) Agro-industrial wastes , Circular economy , Metabolic engineering , Microbial cell factory , Three-carbon platform chemicals
- 관리정보기술 faculty
- 등재 SCIE, SCOPUS
- 발행기관 Elsevier Ltd
- 발행년도 2022
- URI http://www.dcollection.net/handler/ewha/000000191118
- 본문언어 영어
- Published As https://doi.org/10.1016/j.biortech.2022.126797
- PubMed https://pubmed.ncbi.nlm.nih.gov/35122981
초록/요약
At present, mass production of basic and valuable commodities is dependent on linear petroleum-based industries, which ultimately makes the depletion of finite natural reserves and accumulation of non-biodegradable and hazardous wastes. Therefore, an ecofriendly and sustainable solution should be established for a circular economy where infinite resources, such as agro-industrial wastes, are fully utilized as substrates in the production of target value-added chemicals. Hereby, recent advances in metabolic engineering strategies and techniques used in the development of microbial cell factories for enhanced production of three-carbon platform chemicals such as lactic acid, propionic acid, and 3-hydroxypropionic acid are discussed. Further developments and future perspectives in the production of these organic acids from agro-industrial wastes from the dairy, sugar, and biodiesel industries are also highlighted to demonstrate the importance of waste-based biorefineries for organic acid production. © 2022 Elsevier Ltd
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