An unconventional nano-AIEgen originating from a natural plant polyphenol for multicolor bioimaging
- 주제(기타) Chemistry, Multidisciplinary
- 주제(기타) Energy & Fuels
- 주제(기타) Materials Science, Multidisciplinary
- 주제(기타) Physics, Multidisciplinary
- 설명문(일반) [Lu, Lei] Wenzhou Med Univ, Sch & Hosp Stomatol, Wenzhou 325027, Peoples R China; [Lu, Lei; Zhang, Tingting] Southwest Jiaotong Univ, Sch Life Sci & Engn, Sichuan Engn Res Ctr Biomimet Synth Nat Drugs, Chengdu 610031, Peoples R China; [Yang, Mengyao; Kwon, Nahyun; Li, Haidong; Yoon, Juyoung] Ewha Womans Univ, Dept Chem & Nanosci, Seoul 03760, South Korea; [Kim, Youngseo; Park, Sungnam] Korea Univ, Dept Chem, Seoul 02841, South Korea; [Li, Haidong] Dalian Univ Technol, Sch Bioengn, Dalian 116024, Peoples R China
- 등재 SCIE, SCOPUS
- OA유형 gold
- 발행기관 ELSEVIER
- 발행년도 2022
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000191167
- 본문언어 영어
- Published As https://doi.org/10.1016/j.xcrp.2022.100745
초록/요약
Biocompatible aggregation-induced emission (AIE) materials from natural resources are of great interest for a variety of potential applications. Here, we report the unconventional AIE nature of the green tea polyphenol epigallocatechin gallate (EGCG), which is investigated by observing the disappearance and reoccurrence of fluorescence when EGCG is dissolved and recrystallized in aqueous solutions. The intermolecular through-space conjugation and structural rigidification induced by multiple intermolecular H-bonds play critical roles in the AIE phenomenon. This inspires the development of a multicolored, monodisperse, photostable, and non-toxic nano-AIE luminogen (nano-AIEgen), which is simply prepared by polyphenol-amine-based crosslinking in aqueous solutions, demonstrating great potential for living cell bioimaging. Our strategy to develop nano-AIEgens using AIE-active hydrophilic natural products-e.g., plant polyphenols, such as tannic acid, that exhibit similar AIE characteristics-can help push the boundary of the exploration of various novel, large-scale, biocompatible, water-soluble, and degradable AIE materials from natural resources.
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