An Overview of Recent Advancements in Microbial Polyhydroxyalkanoates (PHA) Production from Dark Fermentation Acidogenic Effluents: A Path to an Integrated Bio-Refinery
- 주제(키워드) dark fermentative hydrogen production , volatile fatty acids (VFAs) , polyhydroxyalkanoates (PHA) , biobased production , genetic engineering
- 주제(기타) Polymer Science
- 설명문(일반) [Saratale, Rijuta Ganesh; Kadam, Avinash A.] Dongguk Univ Seoul, Res Inst Biotechnol & Med Converged Sci, Goyang Si 10326, Gyeonggido, South Korea; [Cho, Si-Kyung; Ghodake, Gajanan S.] Dongguk Univ, Dept Biol & Environm Sci, Goyang Si 10326, Gyeonggido, South Korea; [Saratale, Ganesh Dattatraya; Shin, Han-Seung] Dongguk Univ Seoul, Dept Food Sci & Biotechnol, Goyang Si 10326, Gyeonggido, South Korea; [Kumar, Manu] Dongguk Univ Seoul, Dept Life Sci, 32 Dongguk Ro, Goyang Si 10326, Gyeonggi Do, South Korea; [Bharagava, Ram Naresh] Babasaheb Bhimrao Ambedkar Univ, Sch Environm Sci, Dept Environm Microbiol, Vidya Vihar 226025, Uttar Pradesh, India; [Varjani, Sunita] Gujarat Pollut Control Board, Gandhinagar 382010, Gujarat, India; [Palem, Ramasubba Reddy] Dongguk Univ Biomed, Dept Med Biotechnol, Campus 32, Seoul 10326, South Korea; [Mulla, Sikandar I.] REVA Univ, Sch Appl Sci, Dept Biochem, Bangalore 560064, Karnataka, India; [Kim, Dong-Su] Ewha Womans Univ, Dept Environm Sci & Engn, Seoul 03760, South Korea
- 등재 SCIE, SCOPUS
- OA유형 Green Published, gold
- 발행기관 MDPI
- 발행년도 2021
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000191238
- 본문언어 영어
- Published As https://doi.org/10.3390/polym13244297
- PubMed https://pubmed.ncbi.nlm.nih.gov/34960848
초록/요약
Global energy consumption has been increasing in tandem with economic growth motivating researchers to focus on renewable energy sources. Dark fermentative hydrogen synthesis utilizing various biomass resources is a promising, less costly, and less energy-intensive bioprocess relative to other biohydrogen production routes. The generated acidogenic dark fermentative effluent [e.g., volatile fatty acids (VFAs)] has potential as a reliable and sustainable carbon substrate for polyhydroxyalkanoate (PHA) synthesis. PHA, an important alternative to petrochemical based polymers has attracted interest recently, owing to its biodegradability and biocompatibility. This review illustrates methods for the conversion of acidogenic effluents (VFAs), such as acetate, butyrate, propionate, lactate, valerate, and mixtures of VFAs, into the value-added compound PHA. In addition, the review provides a comprehensive update on research progress of VFAs to PHA conversion and related enhancement techniques including optimization of operational parameters, fermentation strategies, and genetic engineering approaches. Finally, potential bottlenecks and future directions for the conversion of VFAs to PHA are outlined. This review offers insights to researchers on an integrated biorefinery route for sustainable and cost-effective bioplastics production.
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