Clustered Detection of Eleven Phthalic Acid Esters by Fluorescence of Graphene Quantum Dots Displaced from Gold Nanoparticles
- 주제(키워드) clustered detection , phthalic acid esters (PAEs) , gold nanoparticles , graphene quantum dots , aptasensor
- 주제(기타) Nanoscience & Nanotechnology
- 주제(기타) Materials Science, Multidisciplinary
- 설명문(일반) [Lim, Hyun Jeong] Yale Univ, Dept Chem & Environm Engn, New Haven, CT 06511 USA; [Lim, Hyun Jeong; Jin, Hyowon; Son, Ahjeong] Ewha Womans Univ, Dept Environm Sci & Engn, Seoul 03760, South Korea; [Chua, Beelee] Korea Univ, Sch Elect Engn, Seoul 02841, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 AMER CHEMICAL SOC
- 발행년도 2022
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000191245
- 본문언어 영어
- Published As https://doi.org/10.1021/acsami.1c21756
- PubMed https://pubmed.ncbi.nlm.nih.gov/35029109
초록/요약
A gold nanoparticle-quenched graphene quantum dot-based aptasensor was developed to perform clustered detection of 11 phthalic acid esters (PAEs). The binding of the target PAEs to the aptasensor frees the graphene quantum dots that are otherwise quenched by the carrier gold nanoparticle. The resultant fluorescence upon excitation is proportional to the number of freed graphene quantum dots and hence the target PAE concentration. The synthesis of the proposed aptasensor was first verified step-by-step via FT-IR measurement, scanning electron microscopy, and fluorescence measurement. Selectivity was evaluated for individual and combined target PAEs and compared against seven non-PAE endocrine disrupting compounds. The proposed aptasensor successfully quantified 11 PAEs in test samples with varying concentrations of 0.001-50 ng PAEs/mL and demonstrated a limit of detection of similar to 4 pg./mL. Finally, the AuNP-gQD aptasensor was employed to detect multiple combinations of commonly regulated PAEs (DBP, DIBP, DEHP, and BBP). The recovery (%) for all four PAEs combination in environmentally relevant concentrations of 0.5, 1, 5, and 10 ng/mL were similar to 100%.
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