Clinical Usefulness of 18F-FET PET in a Pediatric Patient with Suspected Demyelinating Disease
- 주제(키워드) 18F-FET PET/CT , demyelinating disease , encephalomyelitis
- 등재 SCIE, SCOPUS
- 발행기관 Lippincott Williams and Wilkins
- 발행년도 2022
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000193382
- 본문언어 영어
- Published As https://doi.org/10.1097/RLU.0000000000004201
- PubMed https://pubmed.ncbi.nlm.nih.gov/35384903
초록/요약
An 11-year-old boy who presented with headache and progressive right-sided weakness exhibited cortical swelling in the parafalcine area of both frontoparietal high convexity and splenium portion of corpus callosum on brain MRI. This suggested the possibility of encephalopathy, but required differential diagnosis from brain tumor. 18F-FET (O-(2-[18F]fluoroethyl)-l-tyrosine) PET/CT identified increased uptake along the parafalcine area of the frontoparietal lobes and the splenium portion of the corpus callosum. The relatively low target-to-background ratios were more indicative of inflammatory changes such as demyelinating disease. The patient recovered after empirical steroid and immunoglobulin treatment. Clinically, the patient was diagnosed with acute disseminated encephalomyelitis. © 2022 Wolters Kluwer Health, Inc.
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