Ocular Surface and Tear Cytokine Changes after Cataract Surgery in Patients with Type 2 Diabetes
- 주제(키워드) Cataract surgery , cytokines , ocular surface parameters , tear , type 2 diabetes mellitus
- 등재 SCIE, SCOPUS
- 발행기관 Taylor and Francis Ltd.
- 발행년도 2022
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000193653
- 본문언어 영어
- Published As https://doi.org/10.1080/09273948.2022.2088565
초록/요약
Purpose: To evaluate changes in ocular surface indices and tear cytokines after cataract surgery in type 2 diabetic patients. Methods: Ocular surface indices and concentrations of tear cytokines (MCP-1, IL-6, IL-8, and VEGF) were evaluated at baseline and one week and one month postoperatively. Results: Patients (30 diabetic and 30 control) were enrolled. In the diabetic group, changes in ocular symptom and tear breakup time remained until one month postoperatively (P < .05, respectively); in the control group, ocular symptom increased at one week postoperatively (P = .015). MCP-1 level in the diabetic group significantly increased postoperatively (all P < .05); however, in the control group, the IL-8 level was significantly decreased postoperatively (all P < .05). MCP-1 concentration was negatively correlated with TBUT in the diabetic group. Conclusion: Diabetic patients can experience more prominent changes after surgery and these changes were accompanied by an increase of several tear cytokines. © 2022 Taylor & Francis Group, LLC.
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