Bowel Preparation and Subsequent Colonoscopy Is Associated with the Risk of Atrial Fibrillation: A Population-Based Case-Crossover Study
- 주제(키워드) bowel preparation , atrial fibrillation , colonoscopy
- 주제(기타) Health Care Sciences & Services
- 주제(기타) Medicine, General & Internal
- 설명문(일반) [Jung, Yoon Suk] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Div Gastroenterol,Dept Internal Med, Seoul 03181, South Korea; [Jee, Yongho] Ewha Womans Univ, Seoul Hosp, Adv Biomed Res Inst, Seoul 07804, South Korea; [Im, Eui] Yonsei Univ, Coll Med, Dept Internal Med, Div Cardiol, Yongin 16995, South Korea; [Im, Eui] Yongin Severance Hosp, Cardiovasc Ctr, Yongin 16995, South Korea; [Kim, Min-ho] Ewha Womans Univ, Seoul Hosp, Informatizat Dept, Seoul 07804, South Korea; [Moon, Chang Mo] Ewha Womans Univ, Coll Med, Dept Internal Med, Seoul 07985, South Korea; [Moon, Chang Mo] Ewha Womans Univ, Coll Med, Inflammat Canc Microenvironm Res Ctr, Seoul 07804, South Korea
- 등재 SCIE, SCOPUS
- OA유형 gold, Green Published
- 발행기관 MDPI
- 발행년도 2022
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000194615
- 본문언어 영어
- Published As https://doi.org/10.3390/jpm12081207
- PubMed https://pubmed.ncbi.nlm.nih.gov/35893301
초록/요약
This study aimed to clarify the association of the risk of atrial fibrillation (AF) with bowel preparation and subsequent colonoscopy through population-based case-crossover analysis. Patients who developed new-onset AF after undergoing colonoscopy following bowel preparation were included. For each patient, one hazard period and four control periods were matched at specified time windows. Among 189,613 patients with AF, 84 patients (mean age: 72.4 years) finally met the inclusion criteria. Most patients used polyethylene glycol (PEG)-based solutions (2 L PEG + ascorbic acid (n = 56), 4 L PEG (n = 21)) as purgatives and had hypertension (n = 75). A significant association of bowel preparation and colonoscopy with AF occurrence was found in all time windows. The proportion of patients with bowel preparation and colonoscopy was higher during the hazard period than during the control periods. In the 1-, 2-, 4-, 8-, and 12-week time windows, the proportions were 11.9% vs. 4.2%, 13.1% vs. 4.8%, 16.7% vs. 6.3%, 28.6% vs. 11.9%, and 29.8% vs. 14.0%, and the odd ratios (ORs) were 3.11, 3.01, 3.00, 2.96, and 2.61, respectively. Bowel preparation and undergoing colonoscopy was associated with the risk of AF and this examination need to be performed with caution especially in elderly patients with hypertension.
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