Association between Seafood Intake and Cardiovascular Disease in South Korean Adults: A Community-Based Prospective Cohort Study
- 주제(키워드) cardiovascular disease , seafood intake , longitudinal study
- 주제(기타) Nutrition & Dietetics
- 설명문(일반) [Park, Gyu-Hee] Ewha Grad Sch Converging Clin & Publ Hlth, Dept Clin Nutr, Seoul 03760, South Korea; [Cho, Jung-Hee; Lee, Donglim] Korea Maritime Inst, Fisheries Policy Res Div, Busan 49111, South Korea; [Kim, Yangha] Ewha Womans Univ, Dept Nutr Sci & Food Management, Seoul 03760, South Korea; [Kim, Yangha] Ewha Womans Univ, Grad Program Syst Hlth Sci & Engn, Seoul 03760, South Korea
- 등재 SCIE, SCOPUS
- OA유형 gold, Green Published
- 발행기관 MDPI
- 발행년도 2022
- URI http://www.dcollection.net/handler/ewha/000000203123
- 본문언어 영어
- Published As https://doi.org/10.3390/nu14224864
- PubMed https://pubmed.ncbi.nlm.nih.gov/36432548
초록/요약
Cardiovascular disease (CVD) is the most common non-communicable diseases causing 18.6 million deaths worldwide. Several studies have revealed that seafood consumption has a protective effect against CVD. This study investigated the correlation between CVD and seafood intake based on a 10-year follow-up of the Korean Genome and Epidemiology Study (KoGES). The study population, which included 6565 adults age, 55.65 (+/- 8.68), was divided into seafood intake-based tertiles. CVD included myocardial infarction, coronary artery disease, congestive heart failure, cerebrovascular disease, and peripheral vascular disease. At baseline, participants with low seafood intake also had low eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) intakes. Prospectively, hazard ratios (HRs) with 95% confidence intervals (CIs) for CVD were analyzed using Cox proportional hazards regression models. Seafood intake exhibited a significantly inverse relationship with the cumulative CVD incidence over 10 years regardless of sex (women: log-rank test p < 0.001 and men: log-rank test p < 0.0401). The longitudinal association of low seafood intake with the CVD risk was significantly stronger in female participants after adjusting for confounding variables (HR (95% confidence interval (CI)) = 0.718 (0.519-0.993) p-trend = 0.043). These results suggested that seafood consumption potentially ameliorates CVD risk in middle-aged adults.
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