Oral Health and Risk of Retinal Vascular Occlusions: A Nationwide Cohort Study
- 주제(키워드) periodontitis , tooth brushing , oral health , retinal vascular occlusion
- 주제(기타) Health Care Sciences & Services; Medicine, General & Internal
- 설명문(일반) [Chang, Yoonkyung; Kim, Sung-Hee] Ewha Womans Univ, Mokdong Hosp, Dept Neurol, Coll Med, Seoul 07985, South Korea; [Jeon, Jimin; Kim, Jinkwon] Yonsei Univ, Yongin Severance Hosp, Dept Neurol, Coll Med, Yongin 16995, South Korea; [Song, Tae-Jin] Ewha Womans Univ, Seoul Hosp, Dept Neurol, Coll Med, Seoul 07804, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 MDPI
- 발행년도 2023
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000205859
- 본문언어 영어
- Published As https://doi.org/10.3390/jpm13010121
초록/요약
Retinal vascular occlusions are a common cause of visual loss. The association between oral health and the risk of retinal vascular occlusions remains unknown. We investigated whether oral health was associated with the risk of retinal vascular occlusions. We conducted a retrospective cohort study including 138,484 participants who completed a national health screening program with an oral health examination from the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) 2002-2015. Oral health markers, such as the presence of periodontitis, tooth loss, and dental caries, and the frequency of daily tooth brushing, were evaluated. The primary outcome was the occurrence of retinal vascular occlusions up to December 2015. In total, 2533 participants developed retinal vascular occlusions (215 with retinal artery occlusion, 1686 with retinal vein occlusion, 632 with unspecified retinal vascular occlusion). In the multivariable Cox regression analysis, periodontitis was an independent risk factor for retinal vascular occlusions (adjusted hazard ratio: 1.18; 95% confidence interval: 1.02-1.36; p = 0.024). Frequent tooth brushing was negatively associated with the risk of retinal vascular occlusions (adjusted hazard ratio: 0.89; 95% confidence interval: 0.80-0.98; p = 0.022). Improving oral hygiene may contribute to the attenuation of the risk of retinal vascular occlusions.
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