Radiological protection in human research ethics using a case study: toward update of the ICRP Publication 62
- 주제(키워드) medical research involving humans , research ethics , International Commission on Radiological Protection , medical imaging , social value , right to know , dose constraint
- 주제(기타) Environmental Sciences; Public, Environmental & Occupational Health; Nuclear Science & Technology; Radiology, Nuclear Medicine & Medical Imaging
- 설명문(일반) [Kurihara, Chieko] Kanagawa Dent Univ, Yokosuka, Kanagawa1, Japan; [Applegate, Kimberly E.] Univ Kentucky, Coll Med, Dept Radiol, Lexington, KY USA; [Jeong, Jee Hyang] Ewha Womans Univ, Sch Med, Dept Neurol, Seoul, South Korea; [Akahane, Keiichi] Natl Inst Quantum Sci & Technol, Chiba, Japan; [Kang, Keon Wook] Seoul Natl Univ, Coll Med, Dept Nucl Med, Seoul, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 IOP Publishing Ltd
- 발행년도 2023
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000213473
- 본문언어 영어
- Published As https://doi.org/10.1088/1361-6498/ad04f0
- PubMed 37857271
초록/요약
The benefits of biomedical research involving humans are well recognised, along with the need for conformity to international standards of science and ethics. When human research involves radiation imaging procedures or radiotherapy, an extra level of expert review should be provided from the point of view of radiological protection. The relevant publication of the International Commission for Radiological Protection (ICRP) is now three decades old and is currently undergoing an update. This paper aims to provoke discussions on how the risks of radiation dose and the benefits of research should be assessed, using a case study of diagnostic radiology involving volunteers for whom there is no direct benefit. Further, the paper provides the current understanding of key concepts being considered for review and revision-such as the dose constraint and the novel research methods on the horizon, including radiation biology and epidemiology. The analysis revisits the perspectives described in the ICRP Publication 62, and considers the recent progress in both radiological protection ethics and medical research ethics.
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