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Association of typical atrial flutter and cavotricuspid isthmus ablation on clinical recurrence after cryoballoon ablation for atrial fibrillation

  • 주제(키워드) cryoballoon ablation , cavotricuspid isthmus , atrial fibrillation , atrial flutter , radiofrequency ablation
  • 주제(기타) Cardiac & Cardiovascular Systems
  • 설명문(일반) [Jeong, Joo Hee; Lee, Hyoung Seok; Choi, Yun Young; Kim, Yun Gi; Choi, Jong-Il; Kim, Young-Hoon; Shim, Jaemin] Korea Univ, Coll Med, Dept Internal Med, Div Cardiol, Seoul, South Korea; [Jeong, Joo Hee; Lee, Hyoung Seok; Choi, Yun Young; Kim, Yun Gi; Choi, Jong-Il; Kim, Young-Hoon] Anam Hosp, Korea Univ, Seoul, South Korea; [Lim, Hong Euy] Hallym Univ, Coll Med, Div Cardiol, Sacred Heart Hosp, Anyang, South Korea; [Oh, Il-Young] Seoul Natl Univ, Bundang Hosp, Coll Med, Cardiovasc Ctr, Seongnam, South Korea; [Cha, Myung-Jin] Univ Ulsan, Coll Med, Heart Inst, Asan Med Ctr, Seoul, South Korea; [Lee, So-Ryoung] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul Natl Univ Hosp, Seoul, South Korea; [Kim, Ju Youn] Sungkyunkwan Univ, Heart Vasc & Stroke Inst, Samsung Med Ctr, Dept Internal Med,Div Cardiol,Sch Med, Seoul, South Korea; [Kwon, Chang Hee] Konkuk Univ, Med Ctr, Dept Internal Med, Div Cardiol,Sch Med, Seoul, South Korea; [Lee, Sung Ho] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Dept Internal Med, Seoul, South Korea; [Park, Junbeom] Ewha Womans Univ, Sch Med, Dept Cardiol, Seoul, South Korea; [Kim, Ki-Hun] Inje Univ, Coll Med, Haeundae Paik Hosp, Dept Internal Med, Busan, South Korea; [Yang, Pil-Sung] CHA Univ, CHA Bundang Med Ctr, Dept Cardiol, Seongnam, South Korea; [Kim, Jun-Hyung] Chungnam Natl Univ, Chungnam Natl Univ Hosp, Coll Med, Dept Internal Med, Daejeon, South Korea
  • 등재 SCIE, SCOPUS
  • OA유형 Gold Open Access
  • 발행기관 FRONTIERS MEDIA SA
  • 발행년도 2023
  • 총서유형 Journal
  • URI http://www.dcollection.net/handler/ewha/000000213639
  • 본문언어 영어
  • Published As https://doi.org/10.3389/fcvm.2023.1303635
  • PubMed 38162135

초록/요약

Typical atrial flutter commonly occurs in patients with atrial fibrillation (AF). Limited information exists regarding the effects of concurrent atrial flutter on the long-term outcomes of rhythm control. This study investigated the association between concurrent typical atrial flutter and cavotricuspid isthmus (CTI) ablation and the recurrence of atrial arrhythmia. The data were obtained from a multicenter registry of cryoballoon ablation for AF (n = 2,689). Patients who were screened for typical atrial flutter were included in the analysis (n = 1,907). All the patients with typical atrial flutter underwent CTI ablation. The primary endpoint was the late recurrence of atrial arrhythmia, including AF, atrial flutter, and atrial tachycardia. Among the 1,907 patients, typical atrial flutter was detected in 493 patients (25.9%). Patients with concurrent atrial flutter had a lower incidence of persistent AF and a smaller size of the left atrium. Patients with atrial flutter had a significantly lower recurrence rate of atrial arrhythmia (19.7% vs. 29.9%, p < 0.001). In patients with atrial flutter, the recurrence rate of atrial tachycardia or atrial flutter was more frequent (7.3% vs. 4.7%, p = 0.028), but the recurrence rate of AF was significantly lower (17.0% vs. 29.4%, p < 0.001). Atrial flutter has been identified as an independent predictor of the primary endpoint (adjusted hazard ratio, 0.704; 95% confidence interval, 0.548-0.906; p = 0.006). Typical atrial flutter in patients with AF may serve as a positive marker of the recurrence of atrial arrhythmia, and performing CTI ablation in this population is associated with a reduced likelihood of AF recurrence. Performing routine screening and ablation procedures for coexisting atrial flutter may improve the clinical outcomes of AF.

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