Bacterial Etiology in Subacute Cough
- 주제(키워드) Cough , bacteria , polymerase chain reaction , Bordetella pertussis
- 주제(기타) Allergy; Immunology
- 설명문(일반) [Moon, Ji-Yong; Lee, Hyun; Kim, Sang-Heon; Yoon, Ho Joo] Hanyang Univ, Dept Internal Med, Coll Med, Seoul, South Korea; [Kim, Min-Hye] Ewha Womans Univ, Dept Internal Med, Coll Med, Seoul, South Korea; [Song, Woo-Jung] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Allergy & Clin Immunol, Seoul, South Korea; [Lee, Sang Min] Gachon Univ, Gil Med Ctr, Dept Internal Med, Incheon, South Korea; [Kim, Sae-Hoon] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Seongnam, South Korea; [Lee, Byung-Jae] Sungkyunkwan Univ, Dept Med, Samsung Med Ctr, Sch Med, Seoul, South Korea; [Kim, Sang Hoon] Eulji Univ, Nowon Eulji Hosp, Dept Internal Med, Sch Med, Seoul, South Korea
- 등재 SCIE, SCOPUS, KCI등재
- OA유형 Gold Open Access; Green Published
- 발행기관 KOREAN ACAD ASTHMA ALLERGY & CLINICAL IMMUNOLOGY
- 발행년도 2023
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000213753
- 본문언어 영어
- PubMed 37153983
초록/요약
Although postinfectious etiology is the most common cause of subacute cough, there are insufficient data on the epidemiology of associated bacterial infections. We aimed to identify the etiology of bacterial detection in subjects with subacute cough. A multicenter prospective observational study of 142 patients with postinfectious subacute cough was performed between August 2016 and December 2017 in Korea. We obtained 2 nasal swabs from each patient and used a multiplex bacterial polymerase chain reaction (PCR) kit that simultaneously detects Bordetella pertussis, Chlamydophila pneumoniae, Haemophilus influenzae, Legionella pneumophilia, Mycoplasma pneumoniae, and Streptococcus pneumoniae. About 29% (n = 41) of patients with subacute cough were positive for bacterial PCR in nasal swabs. The most common bacteria detected by bacterial PCR was H. influenzae (n = 19, 13.4%), followed by S. pneumoniae (n = 18, 12.7%), B. pertussis (n = 7, 4.9%), M. pneumoniae (n = 3, 2.1%), L. pneumophilia (n = 2, 1.4%), and C. pneumoniae (n = 1, 0.7%). Nine patients had dual positivity for the PCR. In conclusion, bacterial PCR was positive in the nasal swabs of about 29% of subjects with subacute cough, including 5% of positive PCR results for B. pertussis.
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