Effectiveness of transcranial alternating current stimulation for controlling chronic pain: a systematic review
- 주제(키워드) transcranial alternating current stimulation , chronic pain , fibromyalgia , low back pain , migraine , treatment , review
- 주제(기타) Clinical Neurology; Neurosciences
- 설명문(일반) [Chang, Min Cheol] Yeungnam Univ, Coll Med, Dept Rehabil Med, Daegu, South Korea; [Briand, Marie-Michele] Hop Sacre Coeur Montreal, Res Ctr, Div Trauma, CIUSSS Nord de Ille de Montreal, Montreal, PQ, Canada; [Briand, Marie-Michele] Hop Sacre Coeur Montreal, Dept Phys Med & Rehabil, CIUSSS Nord de Ille de Montreal, Montreal, PQ, Canada; [Briand, Marie-Michele; Boudier-Reveret, Mathieu] Univ Montreal, Fac Med, Montreal, PQ, Canada; [Boudier-Reveret, Mathieu] Univ Montreal, Dept Phys Med & Rehabil, Hlth Ctr, Montreal, PQ, Canada; [Yang, Seoyon] Ewha Womans Univ, Seoul Hosp, Sch Med, Dept Rehabil Med, Seoul, South Korea
- 등재 SCIE, SCOPUS
- OA유형 Gold Open Access
- 발행기관 FRONTIERS MEDIA SA
- 발행년도 2023
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000213825
- 본문언어 영어
- Published As https://doi.org/10.3389/fneur.2023.1323520
- PubMed 38192572
초록/요약
BackgroundChronic pain is common, disruptive, and often treatment-resistant. Hence, researchers and clinicians seek alternative therapies for chronic pain. Transcranial alternating current stimulation (tACS) is an emerging neuromodulation technique that non-invasively modulates neural oscillations in the human brain. tACS induces pain relief by allowing the neural network to restore adequate synchronization. We reviewed studies on the effectiveness of tACS in controlling chronic pain.MethodsThe PubMed, SCOPUS, Embase, and Cochrane Library databases were systematically searched for relevant studies published until December 6, 2023. The key search phrase for identifying potentially relevant articles was [(Transcranial Alternating Current Stimulation OR tACS) AND pain]. The following inclusion criteria were applied for article selection: (1) studies involving patients with chronic pain; (2) tACS was applied for controlling pain; and (3) follow-up evaluations were performed to assess the degree of pain reduction after the application of tACS.ResultsWe identified 2,330 potentially relevant articles. After reading the titles and abstracts and assessing eligibility based on the full-text articles, we included four articles in our review. Among the included studies, tACS was used for fibromyalgia in one study, low back pain (LBP) in two studies, and migraine in one study. In the study on fibromyalgia, it did not show a better pain-reducing effect of tACS compared with sham stimulation. Two studies on LBP showed conflicting results. In migraine, tACS showed a positive pain-reducing effect 24-48 h after its application.ConclusionThere is insufficient research to draw a conclusive judgment on the effectiveness of tACS in controlling chronic pain. More studies across various chronic pain-related diseases are required for a definitive conclusion.
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