항암제 과민반응에 대한 탈감작요법의 최신지견
Updates on desensitization for hypersensitivity reactions related to chemotherapy
- 주제(키워드) Immunologic desensitization , Antineoplastic agents , Drug hypersensitivity
- 주제(기타) 소아과학
- 설명문(URI) https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001831953
- 등재 KCI등재
- 발행기관 대한 소아알레르기 호흡기학회
- 발행년도 2013
- URI http://www.dcollection.net/handler/ewha/000000238181
- 본문언어 한국어
초록/요약
As the use of chemotherapeutic agents increased rapidly in recent years, more patients are under the potential risk of chemotherapy related adverse reactions. Multiple regular exposures to the same drug by chemotherapy protocol may increase the risk of sensitization to a chemotherapeutic agent, which can result in hypersensitivity reactions. Once severe hypersensitivity reactions occur, causative drugs should be avoided. However, a substitute with equal efficacy is not always available. When there is no effective alternative, desensitization is a safe tool for maintenance of chemotherapeutic agents causing hypersensitivity reaction. In this review, we introduce the latest knowledge about desensitization protocol for chemotherapeutic agents which are frequently used recently.
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